HES7 Antibody

Datasheet

Code	CSB-PA887160LA01HU
Size	US$166
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Image	IHC image of CSB-PA887160LA01HU diluted at 1:400 and staining in paraffin-embedded human lung cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) HES7 Polyclonal antibody

Uniprot No.

Q9BYE0

Target Names

HES7

Alternative Names

bHLH factor Hes7 antibody; bHLHb37 antibody; Class B basic helix loop helix protein 37 antibody; Class B basic helix-loop-helix protein 37 antibody; Hairy and enhancer of split 7 antibody; hes family bHLH transcription factor 7 antibody; Hes7 antibody; HES7_HUMAN antibody; hHes7 antibody; SCDO4 antibody; Transcription factor HES 7 antibody; Transcription factor HES-7 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Transcription factor HES-7 protein (127-192AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The HES7 Antibody (Product code: CSB-PA887160LA01HU) is Non-conjugated. For HES7 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA887160LB01HU	HES7 Antibody, HRP conjugated	ELISA
FITC	CSB-PA887160LC01HU	HES7 Antibody, FITC conjugated
Biotin	CSB-PA887160LD01HU	HES7 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:200-1:500

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Transcriptional repressor. Represses transcription from both N box- and E box-containing promoters. May with HES1, cooperatively regulate somite formation in the presomitic mesoderm (PSM). May function as a segmentation clock, which is essential for coordinated somite segmentation.

Gene References into Functions

mutation of HES7 is uniquely associated with defects in vertebral, heart and neural tube formation, and this observation will help provide a discriminatory diagnostic guide in patients with SCD, as well as inform molecular genetic testing. PMID: 23897666
MESP2, HES7 and DUSP6 genes may not be involved in the etiopathogenesis of sporadic and non-syndromic CS in Chinese Han population. PMID: 22744456
Two new missense mutations in HES7 in a family with spondylocostal dysostosis. PMID: 20087400
R25W missense mutation of HES7 is causative of Spondylocostal dysostosis. PMID: 18775957

Involvement in disease

Spondylocostal dysostosis 4, autosomal recessive (SCDO4)

Subcellular Location

Nucleus.

Database Links

HGNC: 15977

OMIM: 608059

KEGG: hsa:84667

STRING: 9606.ENSP00000446205

UniGene: Hs.434828

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Service

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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