HES7 Antibody, HRP conjugated

Datasheet
Code CSB-PA887160LB01HU
Size US$299
Uniprot No. Q9BYE0
Immunogen Recombinant Human Transcription factor HES-7 protein (127-192AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Transcriptional repressor. Represses transcription from both N box- and E box-containing promoters. May with HES1, cooperatively regulate somite formation in the presomitic mesoderm (PSM). May function as a segmentation clock, which is essential for coordinated somite segmentation (By similarity).
Form Liquid
Conjugate HRP
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Transcription factor HES-7 (hHes7) (Class B basic helix-loop-helix protein 37) (bHLHb37) (Hairy and enhancer of split 7) (bHLH factor Hes7), HES7, BHLHB37
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Research Area Epigenetics and Nuclear Signaling
Target Names HES7
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Transcriptional repressor. Represses transcription from both N box- and E box-containing promoters. May with HES1, cooperatively regulate somite formation in the presomitic mesoderm (PSM). May function as a segmentation clock, which is essential for coordinated somite segmentation (By similarity).
Involvement in disease Spondylocostal dysostosis 4, autosomal recessive (SCDO4)
Subcellular Location Nucleus
Database Links

HGNC: 15977

OMIM: 608059

KEGG: hsa:84667

STRING: 9606.ENSP00000446205

UniGene: Hs.434828

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