HEXIM2 Antibody

Code CSB-PA010319LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: Rat liver tissue, Mouse kidney tissue
    All lanes: HEXIM2 antibody at 3µg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 33 kDa
    Observed band size: 33 kDa

  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA010319LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) HEXIM2 Polyclonal antibody
Uniprot No.
Target Names
HEXIM2
Alternative Names
Hexamethylene bis-acetamide-inducible protein 2 antibody; Hexamthylene bis-acetamide inducible 2 antibody; HEXI2_HUMAN antibody; hexim 2 antibody; HEXIM2 antibody; L3 antibody; Protein HEXIM2 antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant Human Protein HEXIM2 protein (1-286AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The HEXIM2 Antibody (Product code: CSB-PA010319LA01HU) is Non-conjugated. For HEXIM2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA010319LB01HU HEXIM2 Antibody, HRP conjugated ELISA
FITC CSB-PA010319LC01HU HEXIM2 Antibody, FITC conjugated
Biotin CSB-PA010319LD01HU HEXIM2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. Core component of the 7SK RNP complex: in cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
Gene References into Functions
  1. HEXIM2 can functionally and quantitatively compensate for the loss of HEXIM1 PMID: 15713661
  2. utilization of HEXIM1 or HEXIM2 to bind and inhibit P-TEFb can be differentially regulated in vivo. PMID: 15713662
  3. Positive transcription elongation factor b regulates eukaryotic gene expression at the level of elongation and is controlled by the reversible association with HEXIM2. PMID: 15965233
  4. The tripartite protein-RNA complex formation between Hexim, Cyclin T and 7SK snRNA, was analyzed. PMID: 19883659
Subcellular Location
Nucleus.
Protein Families
HEXIM family
Tissue Specificity
Ubiquitously expressed with higher expression in testis. HEXIM1 and HEXIM2 are differentially expressed.
Database Links

HGNC: 28591

OMIM: 615695

KEGG: hsa:124790

STRING: 9606.ENSP00000302276

UniGene: Hs.56382

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