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Lead Time
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May play an important role in the development of cancers in a broad range of tissues.
Gene References into Functions
Authors propose that HID-1 influences early steps in LDCV formation by controlling dense core formation at the TGN. PMID: 29074564
mammalian HID-1 localized to the medial- and trans- Golgi apparatus as well as the cytosol. PMID: 21337012
Subcellular Location
Cytoplasm. Golgi apparatus membrane; Lipid-anchor. Note=Shuttles between the cytosol and the Golgi apparatus.
Protein Families
Hid-1 family
Tissue Specificity
Expressed in heart, skeletal muscle, colon, spleen, kidney, liver, small intestine and lung. Highest expression is seen in brain and placenta. Loss of expression is seen in some breast, cervical, hepatocellular, lung, thyroid, gastric and renal cell-cance