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HIGD1A Antibody

Datasheet
Code CSB-PA010354GA01HU
Size $600
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Product Details

Uniprot No.
Q9Y241
Target Names
HIGD1A
Alternative Names
Hig1 antibody; HIG1 domain family member 1A antibody; HIG1 domain family; member 1A antibody; HIG1 hypoxia inducible domain family; member 1A antibody; HIG1A_HUMAN antibody; HIGD1A antibody; HIMP1 antibody; Hypoxia-inducible gene 1 protein antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human HIGD1A
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IF
Protocols
ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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HIGD1A Proteins

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Target Background

Function
Proposed subunit of cytochrome c oxidase (COX, complex IV), which is the terminal component of the mitochondrial respiratory chain that catalyzes the reduction of oxygen to water. May play a role in the assembly of respiratory supercomplexes.
Gene References into Functions
  1. Nuclear localization of the mitochondrial factor HIGD1A during metabolic stress. PMID: 23646141
  2. Data indicate that hypoxia-induced gene domain protein-1a (Higd-1a) inhibits Optic atrophy 1 (Opa1) cleavage and is required for mitochondrial fusion by virtue of its interaction with Opa1. PMID: 23878241
  3. depletion of HIG1 increased gamma-secretase activation and enhanced hypoxia-induced mitochondrial dysfunction PMID: 22355194
Subcellular Location
Mitochondrion membrane; Multi-pass membrane protein. Mitochondrion inner membrane.
Database Links

HGNC: 29527

KEGG: hsa:25994

STRING: 9606.ENSP00000398064

UniGene: Hs.593134

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