HNRNPR Antibody

Code CSB-PA010614GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
HNRNPR
Alternative Names
FLJ25714 antibody; Heterogeneous nuclear ribonucleoprotein R antibody; hnRNP R antibody; hnRNP-R antibody; HNRNPR antibody; HNRPR antibody; HNRPR_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human HNRNPR
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of ribonucleosomes, which are complexes of at least 20 other different heterogeneous nuclear ribonucleoproteins (hnRNP). hnRNP play an important role in processing of precursor mRNA in the nucleus.
Gene References into Functions
  1. demonstrated that HNRNPR binds MHC class I mRNAs in their 3' untranslated regions and enhances their stability and their expression; regulation by HNRNPR modulates the cytotoxic activity of NK cell; conclude that HNRNPR acts as a general positive regulator of MHC class I expression PMID: 27194785
  2. SMN is involved in the axonal translocation of hnRNP R and hnRNP R-bound RNA/protein complexes. PMID: 25338097
  3. Data demonstrate that expression levels of hnRNP A1, Q, K, R, and U influence HIV-1 production by persistently infected astrocytes, linking these hnRNPs to HIV replication. PMID: 19808671
  4. Short-term exercise resulted in a significant increase of mRNA expression of genes encoding proteins involved in the formation of precatalytic splisosome: HNRNPR. PMID: 19902070
  5. HNRNPR enhanced transcription from the c-fos promoter. PMID: 19581295
  6. validated occurrence of an unusual TG 3' splice site in intron 7 PMID: 17672918

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Subcellular Location
Nucleus. Microsome. Nucleus, nucleoplasm. Cytoplasm.
Database Links

HGNC: 5047

OMIM: 607201

KEGG: hsa:10236

STRING: 9606.ENSP00000363745

UniGene: Hs.373763

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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