HNRNPUL1 Antibody

Datasheet

Code	CSB-PA010616GA01HU
Size	$600
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q9BUJ2

Target Names

HNRNPUL1

Alternative Names

Adenovirus early region 1B associated protein 5 antibody; Adenovirus early region 1B-associated protein 5 antibody; E130317O14Rik antibody; E1B 55 kDa associated protein 5 antibody; E1B AP5 antibody; E1B-55 kDa-associated protein 5 antibody; E1B-AP5 antibody; E1BAP5 antibody; fb53d10 antibody; fk45c03 antibody; FLJ12944 antibody; Heterogeneous nuclear ribonucleoprotein U-like protein 1 antibody; HNRL1_HUMAN antibody; Hnrnpul1 antibody; HNRPUL1 antibody; MGC36621 antibody; MGC78330 antibody; wu:fb53d10 antibody; wu:fk45c03 antibody; zgc:85971 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human HNRNPUL1

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB,IHC,IF

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Acts as a basic transcriptional regulator. Represses basic transcription driven by several virus and cellular promoters. When associated with BRD7, activates transcription of glucocorticoid-responsive promoter in the absence of ligand-stimulation. Plays also a role in mRNA processing and transport. Binds avidly to poly(G) and poly(C) RNA homopolymers in vitro.

Gene References into Functions

we define the arginines within the RGG/RG motifs as the site of methylation by PRMT1 both in vitro and in vivo. The arginines within the human hnRNPUL1 RGG/RG motifs were substituted with lysines to generate hnRNPUL1(RK). PMID: 26020839
U7 snRNP represses histone gene transcription under cell cycle-arrested conditions. hnRNP UL1 is responsible for U7 snRNP-dependent transcriptional repression of replication-dependent histone genes. PMID: 22451911
Despite the limitations, hnRPUL1 and PARP1 were downregulated in renal cell carcinoma and connected with the prognosis. PMID: 24595077
hnRPUL1 as a new component related to PARP1 in DNA damage response and repair PMID: 23577092
hnRNPUL1 and -2 function downstream of MRN and CtBP-interacting protein (CtIP) to promote recruitment of the BLM helicase to DNA breaks. PMID: 22365830
E1B-AP5 is a novel surface molecule that is involved in the undifferentiated state of human embryonic stem cells PMID: 21083500
Regulation of transcripton by this protein is mediated by complex formation with BRD7 PMID: 12489984
Variants in 2 genes were associated with early-onset myocardial infarct: VAMP8, which is involved in platelet degranulation, and HNRPUL1, which encodes a ribonuclear protein. PMID: 16690874
Taken together, these results define a role for E1B-AP5 in ATR signaling pathways activated during adenovirus infection. PMID: 18480432
Human E1B-AP5 binds to adenovirus E1B-55kDa protein. PMID: 9733834

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Subcellular Location

Nucleus.

Database Links

HGNC: 17011

OMIM: 605800

KEGG: hsa:11100

STRING: 9606.ENSP00000375863

UniGene: Hs.155218

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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