HOXB3 Antibody, FITC conjugated

1. Data indicate a miR-375-HOXB3-CDCA3/DNMT3B regulatory circuitry which contributes to leukemogenesis and suggest a therapeutic strategy of restoring miR-375 expression in Acute myeloid leukemia (AML). PMID: 29439669
2. HOXB3 is degraded by miR-375 in breast cancer cells.HOXB3 plays role in tamoxifen resistance. PMID: 28075453
3. miR-10b might control cell apoptosis, proliferation, migration, and invasion in endometrial cancer via regulation of HOXB3 expression. PMID: 27447302
4. decreased methylation at HOXB3 and HOXB4 was associated with increased gene expression of both HOXB genes specific to the mid-risk AML, while increased DNA methylation at DCC distinctive to the high-risk AML was associated with increased gene expression PMID: 25996682
5. describe familial cases of TH in two generations (proband and his father), in addition to other two sporadic cases. We have found polymorphisms in the HOXB3, HOXD3, and a new synonymous variant, and PITX2 genes PMID: 24127533
6. HoxB3 promote prostate cancer progression by upregulating CDCA3 expression. PMID: 23219899
7. The HOXb3 was only weakly expressed in the inv(7) positive patients. PMID: 15674412
8. RASSF1A silencing strongly correlates with overexpression of HOXB3 and DNMT3B. PMID: 19854132

Show More

Hide All

HGNC: 5114

OMIM: 142966

KEGG: hsa:3213

STRING: 9606.ENSP00000308252

UniGene: Hs.654560