HOXB8 Antibody

Code CSB-PA337596
Size US$166
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  • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal liver tissue, Primary antibody: CSB-PA337596(HOXB8 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes
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Product Details

Uniprot No.
Target Names
HOXB8
Alternative Names
HOXB8 antibody; HOX2D antibody; Homeobox protein Hox-B8 antibody; Homeobox protein Hox-2.4 antibody; Homeobox protein Hox-2D antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthetic peptide of Human HOXB8
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:2000
WB 1:200-1:1000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Gene References into Functions
  1. Knockdown of ZEB2 can inhibit HOXB8-induced migration and invasion capacity, as well as the epithelial-mesenchymal transformation in gastric cancer cells. The results showed that HOXB8 plays an important role in the development and metastasis of gastric carcinoma PMID: 27761656
  2. Results show that FMRP regulates miR196a-mediated repression of HOXB8 via interaction with the AGO2 MID domain. PMID: 24727796
  3. HOXB8 and KLK11 may be classified as valuable biomarkers, as they can predict the effects of FOLFOX4 chemotherapy in primary advanced colorectal cancer patients PMID: 23647300
  4. HOXB5 and HOXB8 are frequently expressed in ovarian serous carcinoma, with anatomic site-related differences for cytoplasmic staining. HOXB8 expression is associated with shorter survival in metastatic serous carcinoma. PMID: 23438671
Subcellular Location
Nucleus.
Protein Families
Antp homeobox family
Database Links

HGNC: 5119

OMIM: 142963

KEGG: hsa:3218

STRING: 9606.ENSP00000239144

UniGene: Hs.514292

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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