HRSP12 Antibody

Datasheet

Code	CSB-PA010744GA01HU
Size	$600
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Product Details
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Target Background

Product Details

Uniprot No.

P52758

Target Names

RIDA

Alternative Names

14.5 kDa translational inhibitor protein antibody; 2-iminobutanoate/2-iminopropanoate deaminase antibody; Heat responsive protein 12 antibody; Heat-responsive protein 12 antibody; Hrsp12 antibody; p14.5 antibody; Perchloric acid soluble protein antibody; PSP antibody; Reactive intermediate imine deaminase A homolog antibody; Ribonuclease UK114 antibody; RIDA antibody; Translational inhibitor p14.5 antibody; Translational inhibitor protein p14.5 antibody; UK114 antibody; UK114 antigen homolog antibody; UK114_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human HRSP12

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB,IHC

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase.; Also promotes endoribonucleolytic cleavage of some transcripts by promoting recruitment of the ribonuclease P/MRP complex. Acts by bridging YTHDF2 and the ribonuclease P/MRP complex. RIDA/HRSP12 binds to N6-methyladenosine (m6A)-containing mRNAs containing a 5'-GGUUC-3' motif: cooperative binding of RIDA/HRSP12 and YTHDF2 to such transcripts lead to recruitment of the ribonuclease P/MRP complex and subsequent endoribonucleolytic cleavage.

Gene References into Functions

x-ray crystallography study of p14.5 PMID: 14997576
analysis of ligand binding sites of protein p14.5 PMID: 16198412

Subcellular Location

Cytoplasm. Nucleus. Peroxisome. Mitochondrion.

Protein Families

RutC family

Tissue Specificity

Expressed predominantly in liver and kidney. Lower levels in lung and brain.

Database Links

HGNC: 16897

OMIM: 602487

KEGG: hsa:10247

STRING: 9606.ENSP00000254878

UniGene: Hs.18426

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Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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