HS1BP3 Antibody

Code CSB-PA010745GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
HS1BP3
Alternative Names
ETM2 antibody; FLJ14249 antibody; H1BP3_HUMAN antibody; HCLS1 binding protein 3 antibody; HCLS1-binding protein 3 antibody; HS1 binding protein 3 antibody; HS1 BP3 antibody; HS1-binding protein 3 antibody; Hs1bp3 antibody; HSP1BP-3 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human HS1BP3
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May be a modulator of IL-2 signaling.
Gene References into Functions
  1. HS1BP3 is localized to ATG16L1- and ATG9-positive autophagosome precursors and we show that HS1BP3 binds phosphatidic acid (PA) through its PX domain. Furthermore, we find the total PA content of cells to be significantly upregulated in the absence of HS1BP3. PMID: 28004827
  2. Results suggest that HS1BP3 regulates apoptosis via HS1 and stimulates AP-1-mediated transcription. PMID: 21699750
  3. The 828C-->G mutation causes a substitution of a glycine for an alanine residue in the HS1-BP3 protein. It was found in 2 unrelated patients with familial essential tremor. PMID: 15699368
  4. HS1PB3 protein is mutated in essential tremor combined with Parkinson disease. PMID: 16116142
  5. Results do not support a role for these DRD3 and HS1BP3 variants in PD. PMID: 19524641

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Database Links

HGNC: 24979

OMIM: 609359

KEGG: hsa:64342

STRING: 9606.ENSP00000305193

UniGene: Hs.531785

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