IDH3G Antibody

Code CSB-PA010993LA01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) IDH3G Polyclonal antibody
Uniprot No.
Target Names
IDH3G
Alternative Names
H IDHG antibody; IDH gamma antibody; IDH3G antibody; IDH3G_HUMAN antibody; Isocitrate dehydrogenase [NAD] subunit gamma antibody; Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial antibody; Isocitrate dehydrogenase 3 (NAD+) gamma antibody; Isocitric dehydrogenase antibody; Isocitric dehydrogenase subunit gamma antibody; mitochondrial antibody; NAD (H) specific isocitrate dehydrogenase gamma subunit antibody; NAD(+) specific ICDH antibody; NAD(+)-specific ICDH subunit gamma antibody; NAD+ specific ICDH antibody; OTTHUMP00000025984 antibody; OTTHUMP00000025985 antibody; OTTHUMP00000025987 antibody; OTTHUMP00000025988 antibody; OTTHUMP00000214764 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial protein (40-393AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The IDH3G Antibody (Product code: CSB-PA010993LA01HU) is Non-conjugated. For IDH3G Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA010993LB01HU IDH3G Antibody, HRP conjugated ELISA
FITC CSB-PA010993LC01HU IDH3G Antibody, FITC conjugated
Biotin CSB-PA010993LD01HU IDH3G Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Regulatory subunit which plays a role in the allosteric regulation of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.
Gene References into Functions
  1. Aspartate-190 is a determinant of IDH gamma subunit affinity for the manganese (MnII) ion, as well as for nicotinamide-adenine dinucleotide (NAD), but is not directly required for the catalytic reaction. PMID: 17432878
Subcellular Location
Mitochondrion.
Protein Families
Isocitrate and isopropylmalate dehydrogenases family
Database Links

HGNC: 5386

OMIM: 300089

KEGG: hsa:3421

STRING: 9606.ENSP00000217901

UniGene: Hs.410197

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