IMPG2 Antibody

Datasheet

Code	CSB-PA011704LA01HU
Size	US$166
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Image	Immunofluorescence staining of Hela cells with CSB-PA011704LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) IMPG2 Polyclonal antibody

Uniprot No.

Q9BZV3

Target Names

IMPG2

Alternative Names

IMPG2 antibody; IPM200 antibody; Interphotoreceptor matrix proteoglycan 2 antibody; Interphotoreceptor matrix proteoglycan of 200 kDa antibody; IPM 200 antibody; Sialoprotein associated with cones and rods proteoglycan antibody; Spacrcan antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Interphotoreceptor matrix proteoglycan 2 protein (616-759AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The IMPG2 Antibody (Product code: CSB-PA011704LA01HU) is Non-conjugated. For IMPG2 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA011704LB01HU	IMPG2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA011704LC01HU	IMPG2 Antibody, FITC conjugated
Biotin	CSB-PA011704LD01HU	IMPG2 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IF

Recommended Dilution

Application	Recommended Dilution
IF	1:50-1:200

Protocols

ELISA Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light-sensitive photoreceptor outer segment. Binds heparin.

Gene References into Functions

IMPG1 and IMPG2 are new causal genes of vitelliform dystrophy, involved in 8% of our families. PMID: 25085631
Mutations in IMPG2 cause a severe form of retinitis pigmentosa with symptoms manifesting in the first 2 decades of life. PMID: 24876279
identification of IMPG2 mutations in autosomal-recessive retinitis pigmentosa; data show that mutations in a structural component of the interphotoreceptor matrix can cause autosomal-recessive retinitis pigmentosa PMID: 20673862
IPM 200 represents the second member of a novel family of retinal proteoglycans suspected to be involved in retinal adhesion and photoreceptor cell survival PMID: 10542133

Involvement in disease

Retinitis pigmentosa 56 (RP56); Macular dystrophy, vitelliform, 5 (VMD5)

Subcellular Location

Photoreceptor outer segment membrane; Single-pass type I membrane protein. Photoreceptor inner segment membrane; Single-pass type I membrane protein. Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix.

Tissue Specificity

Expressed in the retina (at protein level). Expressed by photoreceptors of the interphotoreceptor matrix (IPM) surrounding both rods and cones (at protein level). IPM occupies the subretinal space between the apices of the retinal pigment epithelium and t

Database Links

HGNC: 18362

OMIM: 607056

KEGG: hsa:50939

STRING: 9606.ENSP00000193391

UniGene: Hs.209249

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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