INF2 Antibody

Datasheet
Code CSB-PA637740LA01HU
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Size US$299
Uniprot No. Q27J81
Image
  • IHC image of CSB-PA637740LA01HU diluted at 1:400 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

  • IHC image of CSB-PA637740LA01HU diluted at 1:400 and staining in paraffin-embedded human pancreatic cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Immunogen Recombinant Human Inverted formin-2 protein (926-1047AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA, IHC; Recommended dilution: IHC:1:200-1:500
Relevance Severs actin filaments and accelerates their polymerization and depolymerization.
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Inverted formin-2 (HBEBP2-binding protein C), INF2, C14orf151 C14orf173
Immunogen Species Human
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Research Area Tags & Cell Markers
Target Names INF2
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Severs actin filaments and accelerates their polymerization and depolymerization.
Involvement in disease Focal segmental glomerulosclerosis 5 (FSGS5); Charcot-Marie-Tooth disease, dominant, intermediate type, E (CMTDIE)
Subcellular Location Cytoplasm, perinuclear region
Protein Families Formin homology family
Tissue Specificity Widely expressed. In the kidney, expression is apparent in podocytes and some tubule cells.
Database Links

HGNC: 23791

OMIM: 610982

KEGG: hsa:64423

STRING: 9606.ENSP00000376410

UniGene: Hs.24956

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