INF2 Antibody, Biotin conjugated

Datasheet
Code CSB-PA637740LD01HU
Size US$299
Uniprot No. Q27J81
Protocols ELISA Protocol
Immunogen Recombinant Human Inverted formin-2 protein (926-1047AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Severs actin filaments and accelerates their polymerization and depolymerization.
Form Liquid
Conjugate Biotin
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Inverted formin-2 (HBEBP2-binding protein C), INF2, C14orf151 C14orf173
Immunogen Species Homo sapiens (Human)
Research Area Tags & Cell Markers
Target Names INF2
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Severs actin filaments and accelerates their polymerization and depolymerization.
Involvement in disease Focal segmental glomerulosclerosis 5 (FSGS5); Charcot-Marie-Tooth disease, dominant, intermediate type, E (CMTDIE)
Subcellular Location Cytoplasm, perinuclear region
Protein Families Formin homology family
Tissue Specificity Widely expressed. In the kidney, expression is apparent in podocytes and some tubule cells.
Database Links

HGNC: 23791

OMIM: 610982

KEGG: hsa:64423

STRING: 9606.ENSP00000376410

UniGene: Hs.24956

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