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INTS13 Antibody, FITC conjugated

Datasheet
Code CSB-PA868331LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) INTS13 Polyclonal antibody
Uniprot No.
Q9NVM9
Target Names
INTS13
Alternative Names
asun antibody; ASUN_HUMAN antibody; Cell cycle regulator Mat89Bb homolog antibody; Chromosome 12 open reading frame 11 antibody; FLJ10630 antibody; FLJ10637 antibody; Germ cell tumor 1 antibody; NET48 antibody; Protein asunder homolog antibody; Sarcoma antigen NY SAR 95 antibody; Sarcoma antigen NY-SAR-95 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Integrator complex subunit 13 protein (573-706AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucleus coupling. At G2/M phase, may be required for proper spindle formation and execution of cytokinesis. Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.
Gene References into Functions
  1. ASUN is identified as a functional component of Integrator (INT), a multisubunit complex required for 3'-end processing of small nuclear RNAs. PMID: 23904267
  2. Data suggest that ASUN promotes perinuclear enrichment of dynein at G2/M that facilitates BICD2- and CENP-F-mediated anchoring of dynein to nuclear pore complexes. PMID: 23097494
Subcellular Location
Nucleus. Cytoplasm.
Protein Families
Asunder family
Tissue Specificity
Widely expressed. Tends to be up-regulated in seminomas compared to normal testis.
Database Links

HGNC: 20174

OMIM: 615079

KEGG: hsa:55726

STRING: 9606.ENSP00000261191

UniGene: Hs.505077

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