INTS13 Antibody

Code CSB-PA868331LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: Hela whole cell lysate, K562 whole cell lysate, PC-3 whole cell lysate, 293 whole cell lysate
    All lanes: INTS13 antibody at 3.4µg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 81, 69 kDa
    Observed band size: 81 kDa

  • Immunoprecipitating INTS13 in Hela whole cell lysate
    Lane 1: Rabbit control IgG instead of CSB-PA868331LA01HU in Hela whole cell lysate. For western blotting, a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000)
    Lane 2: CSB-PA868331LA01HU (6µg) + Hela whole cell lysate (500µg)
    Lane 3: Hela whole cell lysate (20µg)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) INTS13 Polyclonal antibody
Uniprot No.
Target Names
INTS13
Alternative Names
asun antibody; ASUN_HUMAN antibody; Cell cycle regulator Mat89Bb homolog antibody; Chromosome 12 open reading frame 11 antibody; FLJ10630 antibody; FLJ10637 antibody; Germ cell tumor 1 antibody; NET48 antibody; Protein asunder homolog antibody; Sarcoma antigen NY SAR 95 antibody; Sarcoma antigen NY-SAR-95 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Integrator complex subunit 13 protein (573-706AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The INTS13 Antibody (Product code: CSB-PA868331LA01HU) is Non-conjugated. For INTS13 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA868331LB01HU INTS13 Antibody, HRP conjugated ELISA
FITC CSB-PA868331LC01HU INTS13 Antibody, FITC conjugated
Biotin CSB-PA868331LD01HU INTS13 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IP
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IP 1:200-1:2000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucleus coupling. At G2/M phase, may be required for proper spindle formation and execution of cytokinesis. Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.
Gene References into Functions
  1. ASUN is identified as a functional component of Integrator (INT), a multisubunit complex required for 3'-end processing of small nuclear RNAs. PMID: 23904267
  2. Data suggest that ASUN promotes perinuclear enrichment of dynein at G2/M that facilitates BICD2- and CENP-F-mediated anchoring of dynein to nuclear pore complexes. PMID: 23097494
Subcellular Location
Nucleus. Cytoplasm.
Protein Families
Asunder family
Tissue Specificity
Widely expressed. Tends to be up-regulated in seminomas compared to normal testis.
Database Links

HGNC: 20174

OMIM: 615079

KEGG: hsa:55726

STRING: 9606.ENSP00000261191

UniGene: Hs.505077

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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