INTS13 Antibody

Code CSB-PA868331LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: Hela whole cell lysate, K562 whole cell lysate, PC-3 whole cell lysate, 293 whole cell lysate
    All lanes: INTS13 antibody at 3.4µg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 81, 69 kDa
    Observed band size: 81 kDa

  • Immunoprecipitating INTS13 in Hela whole cell lysate
    Lane 1: Rabbit control IgG instead of CSB-PA868331LA01HU in Hela whole cell lysate. For western blotting, a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000)
    Lane 2: CSB-PA868331LA01HU (6µg) + Hela whole cell lysate (500µg)
    Lane 3: Hela whole cell lysate (20µg)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) INTS13 Polyclonal antibody
Uniprot No.
Target Names
INTS13
Alternative Names
asun antibody; ASUN_HUMAN antibody; Cell cycle regulator Mat89Bb homolog antibody; Chromosome 12 open reading frame 11 antibody; FLJ10630 antibody; FLJ10637 antibody; Germ cell tumor 1 antibody; NET48 antibody; Protein asunder homolog antibody; Sarcoma antigen NY SAR 95 antibody; Sarcoma antigen NY-SAR-95 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Integrator complex subunit 13 protein (573-706AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The INTS13 Antibody (Product code: CSB-PA868331LA01HU) is Non-conjugated. For INTS13 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA868331LB01HU INTS13 Antibody, HRP conjugated ELISA
FITC CSB-PA868331LC01HU INTS13 Antibody, FITC conjugated
Biotin CSB-PA868331LD01HU INTS13 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IP
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IP 1:200-1:2000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucleus coupling. At G2/M phase, may be required for proper spindle formation and execution of cytokinesis. Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.
Gene References into Functions
  1. ASUN is identified as a functional component of Integrator (INT), a multisubunit complex required for 3'-end processing of small nuclear RNAs. PMID: 23904267
  2. Data suggest that ASUN promotes perinuclear enrichment of dynein at G2/M that facilitates BICD2- and CENP-F-mediated anchoring of dynein to nuclear pore complexes. PMID: 23097494
Subcellular Location
Nucleus. Cytoplasm.
Protein Families
Asunder family
Tissue Specificity
Widely expressed. Tends to be up-regulated in seminomas compared to normal testis.
Database Links

HGNC: 20174

OMIM: 615079

KEGG: hsa:55726

STRING: 9606.ENSP00000261191

UniGene: Hs.505077

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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