KCNG3 Antibody

Code CSB-PA703878
Size US$100
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  • Immunohistochemical analysis of paraffin-embedded Rat BrainTissue using Kv10.1 Rabbit pAb diluted at 1:200.
  • Immunohistochemical analysis of paraffin-embedded Mouse BrainTissue using Kv10.1 Rabbit pAb diluted at 1:200.
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Product Details

Uniprot No.
Target Names
KCNG3
Alternative Names
KCNG3; Potassium voltage-gated channel subfamily G member 3; Voltage-gated potassium channel subunit Kv10.1; Voltage-gated potassium channel subunit Kv6.3
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic Peptide
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
IHC,ELISA
Recommended Dilution
Application Recommended Dilution
IHC 1:100-200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1; this promotes a reduction in the rate of activation and inactivation of the delayed rectifier voltage-gated potassium channel KCNB1.
Gene References into Functions
  1. the correlation between dismal prognosis and Kv10.1 expression to patients with brain metastases or glioblastoma multiforme and, moreover, they strongly suggest a role of tricyclic antidepressants for personalized therapy of brain malignancies. PMID: 26530050
  2. [review] an overview of the current status of data linking K(V)10.1 to cancer, and techniques that could exploit K(V)10.1's properties for the management of cancer PMID: 22204340
  3. These results indicate that Kv6.3 is a novel member of the voltage-gated K(+) channel which functions as a modulatory subunit of the Kv2.1 channel. PMID: 11852086
Subcellular Location
Cell membrane; Multi-pass membrane protein. Cytoplasm.
Protein Families
Potassium channel family, G (TC 1.A.1.2) subfamily, Kv6.3/KCNG3 sub-subfamily
Tissue Specificity
Expressed in the brain, liver, testis, small intestine, colon, thymus and adrenal gland.
Database Links

HGNC: 18306

OMIM: 606767

KEGG: hsa:170850

STRING: 9606.ENSP00000304127

UniGene: Hs.352633

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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