KCTD15 Antibody

Code CSB-PA836301ESR2HU
Size US$166
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Image
  • Western blot
    All lanes: KCTD15 antibody at 8μg/ml
    Lane 1: 293T whole cell lysate
    Lane 2: Hela whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 32, 27 kDa
    Observed band size: 32 kDa

  • Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA836301ESR2HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA836301ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) KCTD15 Polyclonal antibody
Uniprot No.
Target Names
KCTD15
Alternative Names
BTB/POZ domain containing protein KCTD15 antibody; BTB/POZ domain-containing protein kctd15 antibody; KCD15_HUMAN antibody; KCTD 15 antibody; kctd15 antibody; MGC25497 antibody; MGC2628 antibody; Potassium channel tetramerisation domain containing 15 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human BTB/POZ domain-containing protein KCTD15 protein (1-234AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
During embryonic development, interferes with neural crest formation. Inhibits AP2 transcriptional activity by interaction with its activation domain.
Gene References into Functions
  1. The KCTD15 rs287103 T variant allele was associated with increased risk of bulimia nervosa and with scores of psychopathological scales of these patients. PMID: 28948079
  2. SEC16B, MC4R, MAP2K5 and KCTD15 (rs17782313, rs543874, rs2241423 and rs11084753) polymorphisms are associated with the risk for children obesity in China. PMID: 25637721
  3. These data suggest that the non-SUMOylated form of Kctd15 functions in neural crest development. PMID: 24086424
  4. Data show the synthetic effect of SNPs on the indices of adiposity and risk of obesity in Chinese girls, but failed to replicate the effect of five separate variants of SEC16B rs10913469, SH2B1 rs4788102, PCSK1 rs6235, KCTD15 rs29941 and BAT2 rs2844479. PMID: 23121087
  5. results indicate that Kctd15 acts in the embryo at least in part by specifically binding to the activation domain of AP-2alpha, thereby blocking the function of this critical factor in the neural crest induction hierarchy. PMID: 23382213

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Database Links

HGNC: 23297

OMIM: 615240

KEGG: hsa:79047

STRING: 9606.ENSP00000394390

UniGene: Hs.221873

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