KIF21B Antibody

Datasheet

Code	CSB-PA012324LA01HU
Size	US$166
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Image	IHC image of CSB-PA012324LA01HU diluted at 1:300 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) KIF21B Polyclonal antibody

Uniprot No.

O75037

Target Names

KIF21B

Alternative Names

KI21B_HUMAN antibody; KIAA0449 antibody; KIF21B antibody; Kinesin-like protein KIF21B antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Kinesin-like protein KIF21B protein (829-986AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The KIF21B Antibody (Product code: CSB-PA012324LA01HU) is Non-conjugated. For KIF21B Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA012324LB01HU	KIF21B Antibody, HRP conjugated	ELISA
FITC	CSB-PA012324LC01HU	KIF21B Antibody, FITC conjugated
Biotin	CSB-PA012324LD01HU	KIF21B Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:200-1:500

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Plus-end directed microtubule-dependent motor protein which displays processive activity. Is involved in regulation of microtubule dynamics, synapse function and neuronal morphology, including dendritic tree branching and spine formation. Plays a role in lerning and memory. Involved in delivery of gamma-aminobutyric acid (GABA(A)) receptor to cell surface.

Gene References into Functions

Thus, KIF21B combines microtubule-binding and regulatory activities that together constitute an autonomous microtubule pausing factor. PMID: 28290984
KIF21B is associated with ankylosing spondylitis in a Chinese population of Shandong Province PMID: 25149646
KIF21B may play an important role in the pathogenesis of AS in the Chinese population and might be a new therapeutic target for AS. PMID: 24065353
Data show the association of SNPs in KIF21B with multiple sclerosis in a Belgian study population. PMID: 20587413
Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B as susceptibility loci PMID: 20007504

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Subcellular Location

Cytoplasm, cytoskeleton. Cell projection, dendrite. Cell projection, growth cone. Cell projection, axon. Cytoplasmic vesicle.

Protein Families

TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family

Database Links

HGNC: 29442

OMIM: 608322

KEGG: hsa:23046

STRING: 9606.ENSP00000328494

UniGene: Hs.169182

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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