KIF21B Antibody, Biotin conjugated

Code CSB-PA012324LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) KIF21B Polyclonal antibody
Uniprot No.
Target Names
KIF21B
Alternative Names
KI21B_HUMAN antibody; KIAA0449 antibody; KIF21B antibody; Kinesin-like protein KIF21B antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Kinesin-like protein KIF21B protein (829-986AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plus-end directed microtubule-dependent motor protein which displays processive activity. Is involved in regulation of microtubule dynamics, synapse function and neuronal morphology, including dendritic tree branching and spine formation. Plays a role in lerning and memory. Involved in delivery of gamma-aminobutyric acid (GABA(A)) receptor to cell surface.
Gene References into Functions
  1. Thus, KIF21B combines microtubule-binding and regulatory activities that together constitute an autonomous microtubule pausing factor. PMID: 28290984
  2. KIF21B is associated with ankylosing spondylitis in a Chinese population of Shandong Province PMID: 25149646
  3. KIF21B may play an important role in the pathogenesis of AS in the Chinese population and might be a new therapeutic target for AS. PMID: 24065353
  4. Data show the association of SNPs in KIF21B with multiple sclerosis in a Belgian study population. PMID: 20587413
  5. Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B as susceptibility loci PMID: 20007504

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Subcellular Location
Cytoplasm, cytoskeleton. Cell projection, dendrite. Cell projection, growth cone. Cell projection, axon. Cytoplasmic vesicle.
Protein Families
TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family
Database Links

HGNC: 29442

OMIM: 608322

KEGG: hsa:23046

STRING: 9606.ENSP00000328494

UniGene: Hs.169182

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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