KLF13 Antibody

1. Results show that cg07814318 methylation in blood was significantly associated with obesity and correlated with several obesity-related physical and biochemical traits. The exome sequencing of KLF13 gene in blood identified nine SNPs within its gene body, and two SNPs as cis-meQTL of cg07814318. The sequencing variations within KLF13 genes could drive dynamic modifications of obesity-related CpG methylation. PMID: 28508896
2. KLF13 functions as a tumor suppressor protein in PCa, and the pharmacological activation of KLF13 might represent a potential approach for the treatment of prostate cancer. PMID: 29843216
3. Our results suggest the cg07814318 site could be involved in orexigenic processes, and also implicate KLF13 in obesity. Our findings are the first to associate methylation levels in blood with brain activity in obesity-related regions, and further support previous findings between ghrelin, brain activity and genetic differences. PMID: 28194012
4. KLF13 is critical for the activation of the HPV productive life cycle and is likely involved in initiation and progression of cervical cancer. PMID: 27041562
5. Knockdown of either FBW7gamma or GSK3beta by small interfering RNA increases KLF13 expression in resting human T lymphocytes. PMID: 22797700
6. No associations were found between maternal genetic polymorphisms in RANTES (-403G/A) and mother-to-child HIV-1 transmission; plasma, cervical and breastmilk viral loads; or breastmilk chemokine concentrations. PMID: 20518834
7. KLF13 contributes to malignancy in oral cancer cells and may be a useful biomarker fo early detection and da possible target for therapy. PMID: 20539070
8. Data support cross-regulation among BMP2, KLF9, and KLF13 to maintain progesterone sensitivity in stromal cells undergoing differentiation and suggest that loss of this network compromises establishment of uterine receptivity and implantation success. PMID: 20410205
9. protein analysis of BTEB3 and BTEB4 and their binding to CYP1A1 PMID: 12036432
10. functional domains and DNA-binding sequences PMID: 12050170
11. A translational rheostat for RFLAT-1 regulates RANTES expression in T lymphocytes. PMID: 12093895
12. Feedback mechanism for the transcriptional control of the KLF13 gene in the erythroid environment. PMID: 15716005
13. KLF13 is a key regulator of late RANTES expression in T lymphocytes PMID: 17074812
14. Coexpression of PRP4 and KLF13 increases nuclear localization of KLF13 and CCL5 transcription. PMID: 17513757
15. Transient transfection of Kruppel-like factor 4 suppressed LDLR, steroidogenic acute regulatory protein, and CYP11A PMID: 18056793

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HGNC: 13672

OMIM: 605328

KEGG: hsa:51621

STRING: 9606.ENSP00000302456

UniGene: Hs.376443