KLHL18 Antibody

Code CSB-PA012420GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
KLHL18
Alternative Names
FLJ13703 antibody; Kelch like 18 (Drosophila) antibody; Kelch like 18 antibody; Kelch-like protein 18 antibody; KIAA0795 antibody; KLH18_HUMAN antibody; KLHL 18 antibody; KLHL18 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human KLHL18
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC,IF
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL18) E3 ubiquitin ligase complex mediates the ubiquitination of AURKA leading to its activation at the centrosome which is required for initiating mitotic entry. Regulates light-and dark-dependent alpha-transducin localization changes in rod photoreceptors through UNC119 ubiquitination and degradation. Preferentially ubiquitinates the unphosphorylated form of UNC119 over the phosphorylated form. In the presence of UNC119, under dark-adapted conditions alpha-transducin mislocalizes from the outer segment to the inner part of rod photoreceptors which leads to decreased photoreceptor damage caused by light.
Database Links

HGNC: 29120

KEGG: hsa:23276

STRING: 9606.ENSP00000232766

UniGene: Hs.517946

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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