LANCL2 Antibody, FITC conjugated

1. human LANCL2 is a non-transmembrane G protein-coupled receptor susceptible to hormone-induced nuclear translocation. PMID: 27222287
2. Data indicate that lanthionine synthetase C-like 2 (LanCL2) depletion sensitizes cells to apoptosis through down-regulating serine/threonine protein kinase Akt phosphorylation. PMID: 25273559
3. human recombinant LANCL2 binds abscisic acid (ABA) directly and provide the first demonstration of ABA binding to a mammalian ABA receptor. PMID: 22037458
4. Molecular docking studies predict that ABA and other PPAR gamma agonists (e.g., rosiglitazone and pioglitazone) share a binding site on the surface of LANCL2. PMID: 20512604
5. cDNA cloned and characterized. May play a role as a component of a peptide-modifying complex PMID: 11762191
6. Lanthionine synthetase components C-like 2 increases cellular sensitivity to adriamycin by decreasing the expression of P-glycoprotein through a transcription-mediated mechanism. PMID: 12566319
7. Data show that lanthionine synthetase C-like protein (LANCL2) is required for abscisic acid binding on human granulocyte membranes and that LANCL2 is necessary for transduction of the ABA signal into granulocytes and rat insulinoma cells. PMID: 19667068

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HGNC: 6509

OMIM: 612919

KEGG: hsa:55915

STRING: 9606.ENSP00000254770

UniGene: Hs.595384