LAP3 Antibody

Datasheet

Code	CSB-PA012745GA01HU
Size	$600
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

P28838

Target Names

LAP3

Alternative Names

AMPL_HUMAN antibody; Cytosol aminopeptidase antibody; epididymis secretory protein Li 106 antibody; HEL-S-106 antibody; LAP 3 antibody; LAP antibody; LAP-3 antibody; Lap3 antibody; LAPEP antibody; Leucine aminopeptidase 3 antibody; Leucyl aminopeptidase antibody; PEPS antibody; Peptidase S antibody; Proline aminopeptidase antibody; Prolyl aminopeptidase antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human LAP3

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB,IHC

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Cytolosic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. The presence of Zn(2+) ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme. For instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates. Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status.

Gene References into Functions

LAP3 might be a new prognostic factor and be close correlation with glioma cell growth, migration, invasion. PMID: 25453285
our results indicated that up-regulated expression of LAP3 might contribute to the proliferation and metastasis of hepatocellular carcinoma PMID: 25120751
Overexpression of leucine aminopeptidase 3 contributes to malignant development of human esophageal squamous cell carcinoma. PMID: 24477662
results suggest that Lys528 is important for maximal activity of adipocyte-derived LAP by maintaining the appropriate structure of the substrate pocket of the enzyme PMID: 16513116

Subcellular Location

Cytoplasm.

Protein Families

Peptidase M17 family

Database Links

HGNC: 18449

OMIM: 170250

KEGG: hsa:51056

STRING: 9606.ENSP00000226299

UniGene: Hs.570791

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Transmembrane Protein Questionnaire with Gifts

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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