LEPREL2 Antibody

Datasheet

Code	CSB-PA075987
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human rectal cancer tissue using CSB-PA075987(LEPREL2 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human placenta tissue using CSB-PA075987(LEPREL2 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200) Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-3: A549 cells, mouse heart tissue, Hela cells, Primary antibody: CSB-PA075987(LEPREL2 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q8IVL6

Target Names

P3H3

Alternative Names

P3H3 antibody; LEPREL2 antibody; Prolyl 3-hydroxylase 3 antibody; EC 1.14.11.7 antibody; Leprecan-like protein 2 antibody; Protein B antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Fusion protein of Human LEPREL2

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,WB,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:2000-1:5000
WB	1:500-1:2000
IHC	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function

Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linkling of collagen fibrils. Required for normal hydroxylation of lysine residues in type I collagen chains in skin, bone, tendon, aorta and cornea. Required for normal skin stability via its role in hydroxylation of lysine residues in collagen alpha chains and in collagen fibril assembly. Apparently not required for normal prolyl 3-hydroxylation on collagen chains, possibly because it functions redundantly with other prolyl 3-hydroxylases.

Subcellular Location

Endoplasmic reticulum.

Protein Families

Leprecan family

Tissue Specificity

Detected in fetal cartilage (at protein level). Weak expression in heart, lung, ovary and skeletal muscle.

Database Links

HGNC: 19318

OMIM: 610342

KEGG: hsa:10536

STRING: 9606.ENSP00000379951

UniGene: Hs.631655

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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