LHPP Antibody, FITC conjugated

Datasheet

Code	CSB-PA867114HC01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) LHPP Polyclonal antibody

Uniprot No.

Q9H008

Target Names

LHPP

Alternative Names

FLJ44846 antibody; FLJ46044 antibody; HDHD2B antibody; hLHPP antibody; lhpp antibody; LHPP_HUMAN antibody; Phospholysine phosphohistidine inorganic pyrophosphate phosphatase antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Phospholysine phosphohistidine inorganic pyrophosphate phosphatase protein (1-270AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

FITC

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function

Phosphatase that hydrolyzes imidodiphosphate, 3-phosphohistidine and 6-phospholysine. Has broad substrate specificity and can also hydrolyze inorganic diphosphate, but with lower efficiency.

Gene References into Functions

LHPP suppresses cell proliferation and metastasis in cervical cancer, and promotes apoptosis by suppressing AKT activation. PMID: 29944886
in patients with hepatocellular carcinoma, low expression of LHPP correlated with increased tumour severity and reduced overall survival; thus LHPP is a protein histidine phosphatase and tumour suppressor, suggesting that deregulated histidine phosphorylation is oncogenic PMID: 29562234
LHPP is associated with the interplay of risky sexual behaviors and alcohol dependence. PMID: 27531626
Patients with major depressive disorder with LHPP rs35936514 CT/TT genotype have increased activity in certain brain regions. PMID: 27843651
LHPP gene variation is associated with oral cavity and pharyngeal cancer. PMID: 27749845
Lhpp or a product of a collinear brain-specific transcript, therefore, may interact with Htr1a in the pathogenesis of major depression PMID: 18268499

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Subcellular Location

Cytoplasm. Nucleus.

Protein Families

HAD-like hydrolase superfamily

Tissue Specificity

Expressed in brain, and at lower levels in liver and kidney. Detected in thyroid (at protein level). Expressed in liver, kidney and moderately in brain.

Database Links

HGNC: 30042

OMIM: 617231

KEGG: hsa:64077

STRING: 9606.ENSP00000357835

UniGene: Hs.527748

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Oxidative Phosphorylation

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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