LIN9 Antibody

Datasheet
Code CSB-PA716370LA01HU
See More Details Free Antibody trial simple
Size US$299
Uniprot No. Q5TKA1
Image
  • IHC image of CSB-PA716370LA01HU diluted at 1:800 and staining in paraffin-embedded human glioma performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunogen Recombinant Human Protein lin-9 homolog protein (5-103AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA, IHC; Recommended dilution: IHC:1:500-1:1000
Relevance Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition.
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Protein lin-9 homolog (HuLin-9) (hLin-9) (Beta subunit-associated regulator of apoptosis) (TUDOR gene similar protein) (Type I interferon receptor beta chain-associated protein) (pRB-associated protein), LIN9, BARA TGS
Immunogen Species Human
Research Area Epigenetics and Nuclear Signaling
Target Names LIN9
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition.
Subcellular Location Nucleus, nucleoplasm
Protein Families Lin-9 family
Tissue Specificity Expressed in thymus and testis.
Database Links

HGNC: 30830

OMIM: 609375

KEGG: hsa:286826

STRING: 9606.ENSP00000329102

UniGene: Hs.120817

Pathway Cellular senescence

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