LPGAT1 Antibody

Code CSB-PA821685LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA821685LA01HU at dilution of 1:100

  • Western Blot
    Positive WB detected in: HEK293 whole cell lysate, Hela whole cell lysate
    All lanes: LPGAT1 antibody at 3µg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 44 kDa
    Observed band size: 44 kDa

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) LPGAT1 Polyclonal antibody
Uniprot No.
Target Names
LPGAT1
Alternative Names
LPGAT1; FAM34A; KIAA0205; Acyl-CoA:lysophosphatidylglycerol acyltransferase 1; Acyl-CoA:monoacylglycerol acyltransferase LPGAT1
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 protein (151-341AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The LPGAT1 Antibody (Product code: CSB-PA821685LA01HU) is Non-conjugated. For LPGAT1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA821685LB01HU LPGAT1 Antibody, HRP conjugated ELISA
FITC CSB-PA821685LC01HU LPGAT1 Antibody, FITC conjugated
Biotin CSB-PA821685LD01HU LPGAT1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:200-1:3000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the transfert of an acyl group from an acyl-CoA to a lysophosphatidylglycerol (LPG) leading to biosynthesis of phosphatidylglycerol, a precursor for cardiolipin synthesis. Uses various acyl-CoAs and LPGs as substrates but demonstrates a clear preference for long chain saturated fatty acyl-CoAs and oleoyl-CoA as acyl donors. Prefers oleoyl-LPG over palmitoyl-LPG as an acyl receptor and oleoyl-CoA over lauroyl-CoA as an acyl donor. In vitro can also catalyzes the transfert of an acyl group from an acyl-CoA to a monoacylglycerol leading to diacylglycerol synthesis, a precursor of triacylglycerol and plays a role in hepatic triacylglycerol synthesis and secretion. Prefers the sn-2-monoacylglycerol to rac-1-monoacylglycerol as acyl acceptor.
Gene References into Functions
  1. LPGAT1 is a novel gene that influences BMI in Native Americans. PMID: 23505186
  2. human LPGAT1 is an endoplasmic reticulum-associated lysophosphatidylglycerol acyltransferase PMID: 15485873
Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein Families
1-acyl-sn-glycerol-3-phosphate acyltransferase family
Tissue Specificity
Highly expressed in liver and placenta. Also expressed in peripheral blood, lung, kidney and brain. Detected at lower levels in colon.
Database Links

HGNC: 28985

OMIM: 610473

KEGG: hsa:9926

STRING: 9606.ENSP00000355963

UniGene: Hs.744851

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