LRR1 Antibody

Datasheet

Code	CSB-PA836247LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA836247LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA836247LA01HU at dilution of 1:100 Immunofluorescent analysis of HepG2 cells using CSB-PA836247LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) LRR1 Polyclonal antibody

Uniprot No.

Q96L50

Target Names

LRR1

Alternative Names

4 1BB mediated signaling molecule antibody; 4 1BBlrr antibody; 4-1BB-mediated-signaling molecule antibody; 4-1BBlrr antibody; Cyclophilin like 5 antibody; Leucine-rich repeat protein 1 antibody; LLR1_HUMAN antibody; LRR 1 antibody; LRR repeat protein 1 antibody; LRR-1 antibody; LRR-repeat protein 1 antibody; LRR1 antibody; MGC20689 antibody; peptidylprolyl isomerase (cyclophilin) like 5 antibody; Peptidylprolyl isomerase like 5 antibody; Peptidylprolyl isomerase-like 5 antibody; PPIL5 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Leucine-rich repeat protein 1 protein (18-159AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The LRR1 Antibody (Product code: CSB-PA836247LA01HU) is Non-conjugated. For LRR1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA836247LB01HU	LRR1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA836247LC01HU	LRR1 Antibody, FITC conjugated
Biotin	CSB-PA836247LD01HU	LRR1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

May negatively regulate the 4-1BB-mediated signaling cascades which result in the activation of NK-kappaB and JNK1. Probable substrate recognition subunit of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Gene References into Functions

Results identify the CRL2(LRR-1) ubiquitin ligase as a conserved regulator of Cip/Kip CKIs that promotes the degradation of C. elegans CKI-1 and human p21. PMID: 21074724

Tissue Specificity

Ubiquitous. Maximal expression was seen in the heart and skeletal muscle and minimal expression seen in the kidney.

Database Links

HGNC: 19742

OMIM: 609193

KEGG: hsa:122769

STRING: 9606.ENSP00000298288

UniGene: Hs.451090

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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