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MAJIN Antibody, Biotin conjugated

Datasheet
Code CSB-PA659444LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MAJIN Polyclonal antibody
Uniprot No.
Q3KP22
Target Names
MAJIN
Alternative Names
MAJIN antibody; C11orf85Membrane-anchored junction protein antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Membrane-anchored junction protein (1-216AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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MAJIN Proteins

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Target Background

Function
Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homologous pairing and synapsis. Component of the MAJIN-TERB1-TERB2 complex, which promotes telomere cap exchange by mediating attachment of telomeric DNA to the inner nuclear membrane and replacement of the protective cap of telomeric chromosomes: in early meiosis, the MAJIN-TERB1-TERB2 complex associates with telomeric DNA and the shelterin/telosome complex. During prophase, the complex matures and promotes release of the shelterin/telosome complex from telomeric DNA. In the complex, MAJIN acts as the anchoring subunit to the nucleus inner membrane. MAJIN shows DNA-binding activity, possibly for the stabilization of telomere attachment on the nucleus inner membrane.
Subcellular Location
Nucleus inner membrane; Single-pass membrane protein. Chromosome, telomere.
Protein Families
MAJIN family
Database Links

HGNC: 27441

OMIM: 617130

KEGG: hsa:283129

UniGene: Hs.567793

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