MAJIN Antibody, FITC conjugated

Code CSB-PA659444LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MAJIN Polyclonal antibody
Uniprot No.
Target Names
MAJIN
Alternative Names
MAJIN antibody; C11orf85Membrane-anchored junction protein antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Membrane-anchored junction protein (1-216AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homologous pairing and synapsis. Component of the MAJIN-TERB1-TERB2 complex, which promotes telomere cap exchange by mediating attachment of telomeric DNA to the inner nuclear membrane and replacement of the protective cap of telomeric chromosomes: in early meiosis, the MAJIN-TERB1-TERB2 complex associates with telomeric DNA and the shelterin/telosome complex. During prophase, the complex matures and promotes release of the shelterin/telosome complex from telomeric DNA. In the complex, MAJIN acts as the anchoring subunit to the nucleus inner membrane. MAJIN shows DNA-binding activity, possibly for the stabilization of telomere attachment on the nucleus inner membrane.
Subcellular Location
Nucleus inner membrane; Single-pass membrane protein. Chromosome, telomere.
Protein Families
MAJIN family
Database Links

HGNC: 27441

OMIM: 617130

KEGG: hsa:283129

UniGene: Hs.567793

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