MAST2 Antibody

Datasheet

Code	CSB-PA003196
Size	US$119
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Image	Western Blot analysis of 293 cells using MAST205 Polyclonal Antibody
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Product Details
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Target Background

Product Details

Uniprot No.

Q6P0Q8

Target Names

MAST2

Alternative Names

EC 2.7.11.1 3 antibody; FLJ39200 antibody; KIAA0807 antibody; MAST 2 antibody; MAST 205 antibody; Mast2 antibody; MAST2_HUMAN antibody; Microtubule associated serine/threonine kinase 2 antibody; Microtubule associated testis specific serine/threonine protein kinase antibody; Microtubule-associated serine/threonine-protein kinase 2 antibody; MTSSK antibody; OTTHUMP00000009697 2 antibody; OTTHUMP00000046616 antibody; RP4 533D7.1 antibody; RP4-533D7.1 2 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Synthesized peptide derived from the Internal region of Human MAST205.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

WB, IHC, IF, ELISA

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:100-1:300
IF	1:200-1:1000
ELISA	1:40000

Protocols

Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation.

Gene References into Functions

we observed 3 case-specific duplications of the autosomal gene MAST2, and in a replication phase we found another 11 duplications PMID: 26203179
Viral and PTEN peptide interactions to MAST2-PDZ occur via a unique kinetic step which involves both canonical C-terminal PBM binding and N-terminal anchoring. PMID: 25942057
MAST2 gene rearrangements occur in invasive breast carcinoma. PMID: 24140425
MAST205 plays an important role in regulating CFTR expression and function PMID: 23504457
The MAST2 sequence at the 5' end of SVA(F1) acts as a positive transcriptional regulator in human germ cells. PMID: 22609064
Recruitment of a MAST2 CpG island was most likely beneficial to the hybrid retrotransposons because it could significantly increase retrotransposition frequency. PMID: 19961423
Studies report the identification of a new subfamily of SVA, which apparently formed after an alternative splicing event where the first exon of the MAST2 gene spliced into an intronic SVA and subsequently retrotransposed. PMID: 19635844

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Subcellular Location

Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Recruited to the sub-membranous area on interaction with CDHR2.

Protein Families

Protein kinase superfamily, AGC Ser/Thr protein kinase family

Tissue Specificity

Abundant in the testis.

Database Links

HGNC: 19035

OMIM: 612257

KEGG: hsa:23139

STRING: 9606.ENSP00000354671

UniGene: Hs.319481

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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