MCF2 Antibody, Biotin conjugated

Code CSB-PA013579LD01HU
Size US$299

Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) MCF2 Polyclonal antibody
Uniprot No. P10911
Target Names MCF2
Alternative Names Proto-oncogene DBL (Proto-oncogene MCF-2) [Cleaved into: MCF2-transforming protein; DBL-transforming protein], MCF2, DBL
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Proto-oncogene DBL protein (705-925AA)
Immunogen Species Homo sapiens (Human)
Conjugate Biotin
Clonality Polyclonal
Isotype IgG
Purification Method Antigen Affinity Purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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Target Data

Function Guanine nucleotide exchange factor (GEF) that modulates the Rho family of GTPases. Promotes the conversion of some member of the Rho family GTPase from the GDP-bound to the GTP-bound form. Isoform 1 exhibits no activity toward RHOA, RAC1 or CDC42. Isoform 2 exhibits decreased GEF activity toward CDC42. Isoform 3 exhibits a weak but significant activity toward RAC1 and CDC42. Isoform 4 exhibits significant activity toward RHOA and CDC42. The truncated DBL oncogene is active toward RHOA, RAC1 and CDC42.
Involvement in disease MCF2 and DBL represent two activated versions of the same proto-oncogene.
Subcellular Location Cytoplasm, SUBCELLULAR LOCATION: Isoform 1: Membrane, SUBCELLULAR LOCATION: Isoform 3: Membrane
Protein Families MCF2 family
Tissue Specificity Isoform 1 is expressed only in brain. Isoform 3 is expressed in heart, kidney, spleen, liver and testis. Isoform 4 is expressed in brain, heart, kidney, testis, placenta, stomach and peripheral blood. The protein is detectable in brain, heart, kidney, int
Database Links

HGNC: 6940

OMIM: 311030

KEGG: hsa:4168

STRING: 9606.ENSP00000430276

UniGene: Hs.387262

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