MGAT4B Antibody, HRP conjugated

Code CSB-PA890781LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MGAT4B Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
3-D-mannoside beta-1 antibody; 3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B antibody; 4-N-acetylglucosaminyltransferase IVb antibody; Alpha 1 3 mannosyl glycoprotein beta 1 4 N acetylglucosaminyltransferase antibody; Alpha-1 antibody; Aminyltransferase antibody; GlcNAc T IVb antibody; GlcNAc-T IVb antibody; GNT IV antibody; GNT IVB antibody; GnT-IVb antibody; GNTIV antibody; GNTIVB antibody; Mannosyl (alpha 1 3) glycoprotein beta 1 4 N acetylglucosaminyltransferase isozyme B antibody; MGAT 4B antibody; mgat4b antibody; MGT4B_HUMAN antibody; N acetylglucosaminyltransferase IVb antibody; N glycosyl oligosaccharide glycoprotein antibody; N glycosyl oligosaccharide glycoprotein N acetylglucosaminyltransferase IVb antibody; N-acetylglucosaminyltransferase IVb antibody; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb antibody; UDP N acetylglucosamine alpha 1 3 D mannoside beta 1 4 N acetylglucosaminyltransferase IV antibody; UDP N acetylglucosamine alpha 1 3 D mannoside beta 1 4 N acetylglucosaminyltransferase IVb antibody; UDP-N-acetylglucosamine: alpha-1 antibody
Raised in
Species Reactivity
Recombinant Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B protein (380-522AA)
Immunogen Species
Homo sapiens (Human)
Purification Method
>95%, Protein G purified
It differs from different batches. Please contact us to confirm it.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Tested Applications
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N-glycan biosynthesis.
Gene References into Functions
  1. UDP-galactose (SLC35A2) and UDP-N-acetylglucosamine (SLC35A3) Transporters Form Glycosylation-related Complexes with Mannoside Acetylglucosaminyltransferases (Mgats). PMID: 25944901
  2. analysis of expression of N-acetylglucosaminyltransferase-IVa and IVb (GnT-IVa and b) in pancreatic cancer PMID: 16434023
  3. GnT-IVa is more active than GnT-IVb under physiological conditions and it primarily contributes to the biosynthesis of N-glycans. PMID: 17006639
  4. We investigated mRNA levels of glycosyltransferases, namely, N-acetylglucosaminyltransferase a (GnT)-IVb, and found that (GnT)-IVb expression was increased in HLE-cells Epirubicin resistant. PMID: 17488527
Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein Families
Glycosyltransferase 54 family
Tissue Specificity
Widely expressed. Strongly overexpressed in pancreatic cancer.
Database Links

HGNC: 7048

OMIM: 604561

KEGG: hsa:11282

STRING: 9606.ENSP00000338487

UniGene: Hs.567419

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