MGST2 Antibody

Datasheet

Code	CSB-PA013792LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA013792LA01HU at dilution of 1:100 Immunofluorescent analysis of HepG2 cells using CSB-PA013792LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) MGST2 Polyclonal antibody

Uniprot No.

Q99735

Target Names

MGST2

Alternative Names

MGST2; GST2; Microsomal glutathione S-transferase 2; Microsomal GST-2; Glutathione peroxidase MGST2; Leukotriene C4 synthase MGST2; Microsomal glutathione S-transferase II; Microsomal GST-II

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Microsomal glutathione S-transferase 2 protein (27-57AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The MGST2 Antibody (Product code: CSB-PA013792LA01HU) is Non-conjugated. For MGST2 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA013792LB01HU	MGST2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA013792LC01HU	MGST2 Antibody, FITC conjugated
Biotin	CSB-PA013792LD01HU	MGST2 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Catalyzes several different glutathione-dependent reactions. Catalyzes the glutathione-dependent reduction of lipid hydroperoxides, such as 5-HPETE. Has glutathione transferase activity, toward xenobiotic electrophiles, such as 1-chloro-2, 4-dinitrobenzene (CDNB). Catalyzes also the conjugation of leukotriene A4 with reduced glutathione to form leukotriene C4 (LTC4). Involved in oxidative DNA damage induced by ER stress and anticancer agents by activating LTC4 biosynthetic machinery in nonimmune cells.

Gene References into Functions

Trimeric microsomal protein MGST2 displays one third of the sites reactivity. PMID: 26066610
characterized the substrate specificity and catalytic properties of purified MGST2 by steady-state and pre-steady-state kinetic experiments PMID: 23409838
A large Chinese sample of psoriasis did not provide any supporting evidence for MGST2 to be the psoriasis susceptibility gene within the PSORS9 locus. PMID: 16773312

Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane; Multi-pass membrane protein.

Protein Families

MAPEG family

Tissue Specificity

Liver, spleen, skeletal muscle, heart, adrenals, pancreas, prostate, testis, fetal liver, and fetal spleen. Very low expression in lung, brain, placenta and bone marrow. Abundantly expressed in human umbilical vein endothelial cells (at protein level).

Database Links

HGNC: 7063

OMIM: 601733

KEGG: hsa:4258

STRING: 9606.ENSP00000265498

UniGene: Hs.81874

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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