MIB2 Antibody, HRP conjugated

1. Missense p.V742G variant in MIB2 is associated with left ventricle hypertrabeculation/non-compaction and Menetrier-like gastropathy. PMID: 28013292
2. Here, we report a novel interaction between CYLD and MIB2 that supports the hypothesis that the CYLD/MIB2 interaction might play a pathogenic role in human cancer. PMID: 25565632
3. identify MIB2 as a novel component of the activated BCL10 signaling complex and a missing link in the BCL10-dependent NF-kappaB signaling pathway. PMID: 21896478
4. Mib2 has functional similarities to Mib1, but might have distinct roles in Notch signaling as an E3 ubiquitin ligase PMID: 15824097
5. Skeletrophin, a novel RING molecule controlled by the chromatin remodeling complex, is down-regulated in melanoma. PMID: 15869411
6. skeletrophin is a novel ubiquitin ligase that targets the intracellular region of Jagged-2 and is aberrantly overexpressed in multiple myeloma cells. PMID: 15920166
7. skeletrophin might be a novel suppressor factor for melanoma invasion PMID: 16715130
8. Data identify Mind bomb-2 as an E3 ubiquitin ligase that interacts with and ubiquitinates the NR2B subunit of the NMDAR in mammalian cells. PMID: 17962190

Show More

Hide All

HGNC: 30577

OMIM: 611141

KEGG: hsa:142678

STRING: 9606.ENSP00000426103

UniGene: Hs.135805