MIER1 Antibody

1. Biochemical analysis of the BAHD1-associated multiprotein complex identifies MIER proteins as novel partners of BAHD1 and suggests that BAHD1-MIER interaction forms a hub for histone deacetylases and methyltransferases PMID: 26938916
2. Insulin and IGF-1 alter the subcellular localization of MIER1alpha in breast carcinoma cells. PMID: 26281834
3. nuclear targeting of MIER1alpha requires an intact ELM2 domain and is dependent on interaction with HDAC1/2 PMID: 24376786
4. the first immunohistochemical study of the MIER1alpha protein expression pattern in human tissues, is reported. PMID: 23277184
5. Differential splicing alters subcellular localization of the alpha but not beta isoform of the MIER1 transcriptional regulator in breast cancer cells PMID: 22384264
6. Results demonstrate that alternate use of a facultative intron regulates the subcellular localization of hMI-ER1 proteins and this may have important implications for hMI-ER1 function. PMID: 12242014
7. we investigated the role of hMI-ER1alpha and hMI-ER1beta in the regulation of transcription.We demonstrate that this repressor activity is due to interaction and recruitment of a trichostatin A-sensitive histone deacetylase 1 (HDAC1). PMID: 12482978
8. the association of hMI-ER1 with Sp1 represents a novel mechanism for the negative regulation of Sp1 target promoters PMID: 15117948
9. Loss of nuclear MI-ER1 alpha might contribute to the development of invasive breast carcinoma PMID: 18665173

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HGNC: 29657

KEGG: hsa:57708

STRING: 9606.ENSP00000383820

UniGene: Hs.605432