MLNR Antibody

Code CSB-PA224944
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA224944(MLNR Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
Alternative Names
MLNR; GPR38; MTLR; MTLR1; Motilin receptor; G-protein coupled receptor 38
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide of Human MLNR
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
IHC 1:25-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Receptor for motilin.
Gene References into Functions
  1. data support important roles of new regions in the TM domains of the motilin receptor for erythromycin action, suggesting differential mechanisms of actions by peptidyl and non-peptidyl ligands PMID: 23142315
  2. The data suggested that in species expressing both motilin-MR and ghrelin-GHSR, there is a compensatory relationship in vivo. PMID: 22465164
  3. The motilin pharmacophore in CHO cells expressing the human motilin receptor PMID: 12054506
  4. motilin receptor extracellular domains have roles in peptide and non-peptidyl agonist binding and activity PMID: 16531413
  5. action by different chemical classes of agonists that are known to interact with distinct regions of the motilin receptor likely yield a common activation state of the cytosolic face of this receptor PMID: 18032475
  6. The motilin receptor is expressed in human colonic and ileal smooth muscle. Further, motilin receptor expression was also shown in the mucosa. PMID: 18183601
  7. Desensitization and internalization of MLNR is independent of the C-terminal tail. PMID: 18420306

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Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
G-protein coupled receptor 1 family
Tissue Specificity
Expressed only in thyroid, stomach, and bone marrow.
Database Links

HGNC: 4495

OMIM: 602885

KEGG: hsa:2862

STRING: 9606.ENSP00000218721

UniGene: Hs.248126

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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