MNDA Antibody

1. MFC adds significant information on dyspoiesis in the diagnostic work up for MDS and provides prognostic information. MNDA expression can be assessed by MFC and may facilitate evaluation of dyspoiesis when added to MDS MFC panels. PMID: 26184452
2. MNDA expression is an independent marker for the evaluation of dyspoiesis and may be added to the standard panel for quantitative assessment by FCM. PMID: 26822549
3. Studied the HIN domain of recombinant myeloid nuclear differentiation antigen (MNDA). PMID: 24557068
4. these data support the inclusion of MNDA in the diagnostic evaluation of extramedullary B-cell lymphomas, particularly those in which the differential diagnosis is between low-grade follicular lymphoma and marginal zone lymphoma. PMID: 24925224
5. Myeloid antigen expression is a predictor of a poor response to chemotherapy, and an adverse prognostic factor in adult T-lymphoblastic lymphoma, but not in children with T-LBL. PMID: 20193116
6. Retroviral mediated expression of the human myeloid nuclear antigen in a null cell line upregulates Dlk1 expression PMID: 12112016
7. variation in MNDA expression appeared to change with phenotypic specialization of monocytes in atherosclerosis consistent with its association with inflammation and suspected roles in regulating gene expression or in mediating cell death PMID: 15778972
8. MNDA has a role regulating programmed cell death in myeloid progenitor cells, and that its down-regulation in myelodysplastic syndromes is related to granulocyte-macrophage progenitor cell sensitivity to TRAIL-induced programmed cell death. PMID: 16651415
9. MNDA expression is a useful tool for the recognition of nodal marginal zone lymphoma PMID: 19474799

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HGNC: 7183

OMIM: 159553

KEGG: hsa:4332

STRING: 9606.ENSP00000357123

UniGene: Hs.153837