MOCOS Antibody

Code CSB-PA014702GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
MOCOS
Alternative Names
MOCOS antibody; Molybdenum cofactor sulfurase antibody; MCS antibody; MOS antibody; MoCo sulfurase antibody; hMCS antibody; EC 2.8.1.9 antibody; Molybdenum cofactor sulfurtransferase antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human MOCOS
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. In vitro, the C-terminal domain is able to reduce N-hydroxylated prodrugs, such as benzamidoxime.
Gene References into Functions
  1. MOCOS sulfurates the molybdenum cofactor of xanthine oxidase (XDH) and aldehyde oxidase 1 (AOX1), which is required for their activities. PMID: 22495427
  2. Two mutations, both in the N-terminal domain of the Human Molybdenum Cofactor Sulfurase (HMCS), were reported in patients with type II xanthinuria. PMID: 17368066
Involvement in disease
Xanthinuria 2 (XAN2)
Protein Families
Class-V pyridoxal-phosphate-dependent aminotransferase family, MOCOS subfamily
Database Links

HGNC: 18234

OMIM: 603592

KEGG: hsa:55034

STRING: 9606.ENSP00000261326

UniGene: Hs.405028

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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