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MRGPRX2 polyclonal antibody CSB-PA839361LA01HU was produced in the rabbit immunized by using the Recombinant Human Mas-related G-protein coupled receptor member X2 protein (286-330AA) as the immunogen. The target protein MRGPRX2 is a mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core. Diseases associated with MRGPRX2 include Ceftazidime Allergy and Cephalosporin Allergy.
This Rabbit anti-Homo sapiens (Human) MRGPRX2 Polyclonal antibody was tested in the ELISA, WB and IF applications. The non-conjugated IgG got purified by protein G and reached up to 95% in purity. It reacts with the MRGPRX2 proteins of human or mouse-origin and may be used to detect the endogenous levels of MRGPRX2 protein.
|Full Product Name||Rabbit anti-Homo sapiens (Human) MRGPRX2 Polyclonal antibody|
MRGPRX2; MRGX2; Mas-related G-protein coupled receptor member X2
|Species Reactivity||Human, Mouse|
|Immunogen||Recombinant Human Mas-related G-protein coupled receptor member X2 protein (286-330AA)|
|Immunogen Species||Homo sapiens (Human)|
The MRGPRX2 Antibody (Product code: CSB-PA839361LA01HU) is Non-conjugated. For MRGPRX2 Antibody with conjugates, please check the following table.
|Purification Method||>95%, Protein G purified|
|Concentration||It differs from different batches. Please contact us to confirm it.|
|Buffer||Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
|Tested Applications||ELISA, WB, IF|
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol
|Troubleshooting and FAQs||Antibody FAQs|
|Storage||Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.|
|Lead Time||Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.|
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Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core. Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction. Acts as a receptor for a number of other ligands, including peptides and alkaloids, such as cortistatin-14, proadrenomedullin N-terminal peptides PAMP-12 and, at lower extent, PAMP-20, antibacterial protein LL-37, PMX-53 peptide, beta-defensins, and complanadine A.
|Gene References into Functions||
|Subcellular Location||Cell membrane; Multi-pass membrane protein.|
|Protein Families||G-protein coupled receptor 1 family, Mas subfamily|
|Tissue Specificity||Mainly expressed in mast cells. Has a limited expression profile, both peripheral and within the central nervous system, with highest levels in dorsal root ganglion. Detected in blood vessels, scattered lymphocytes, and gastrointestinal ganglia (at protei|