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| Code | CSB-PA839361LA01HU |
| Size | US$299 |
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| Description |
MRGPRX2 polyclonal antibody CSB-PA839361LA01HU was produced in the rabbit immunized by using the Recombinant Human Mas-related G-protein coupled receptor member X2 protein (286-330AA) as the immunogen. The target protein MRGPRX2 is a mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core. Diseases associated with MRGPRX2 include Ceftazidime Allergy and Cephalosporin Allergy.
This Rabbit anti-Homo sapiens (Human) MRGPRX2 Polyclonal antibody was tested in the ELISA, WB and IF applications. The non-conjugated IgG got purified by protein G and reached up to 95% in purity. It reacts with the MRGPRX2 proteins of human or mouse-origin and may be used to detect the endogenous levels of MRGPRX2 protein. |
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| Full Product Name | Rabbit anti-Homo sapiens (Human) MRGPRX2 Polyclonal antibody | ||||||
| Uniprot No. | Q96LB1 | ||||||
| Target Names | MRGPRX2 | ||||||
| Alternative Names |
MRGPRX2; MRGX2; Mas-related G-protein coupled receptor member X2
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| Raised in | Rabbit | ||||||
| Species Reactivity | Human, Mouse | ||||||
| Immunogen | Recombinant Human Mas-related G-protein coupled receptor member X2 protein (286-330AA) | ||||||
| Immunogen Species | Homo sapiens (Human) | ||||||
| Conjugate | Non-conjugated The MRGPRX2 Antibody (Product code: CSB-PA839361LA01HU) is Non-conjugated. For MRGPRX2 Antibody with conjugates, please check the following table. |
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| Clonality | Polyclonal | ||||||
| Isotype | IgG | ||||||
| Purification Method | >95%, Protein G purified | ||||||
| Concentration | It differs from different batches. Please contact us to confirm it. | ||||||
| Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
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| Form | Liquid | ||||||
| Tested Applications | ELISA, WB, IF | ||||||
| Recommended Dilution |
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| Protocols | ELISA Protocol Western Blotting(WB) Protocol Immunofluorescence (IF) Protocol |
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| Troubleshooting and FAQs | Antibody FAQs | ||||||
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | ||||||
| Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
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| Function |
Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core. Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction. Acts as a receptor for a number of other ligands, including peptides and alkaloids, such as cortistatin-14, proadrenomedullin N-terminal peptides PAMP-12 and, at lower extent, PAMP-20, antibacterial protein LL-37, PMX-53 peptide, beta-defensins, and complanadine A.
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| Gene References into Functions |
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| Subcellular Location | Cell membrane; Multi-pass membrane protein. |
| Protein Families | G-protein coupled receptor 1 family, Mas subfamily |
| Tissue Specificity | Mainly expressed in mast cells. Has a limited expression profile, both peripheral and within the central nervous system, with highest levels in dorsal root ganglion. Detected in blood vessels, scattered lymphocytes, and gastrointestinal ganglia (at protei |
| Database Links |
HGNC: 17983 OMIM: 607228 KEGG: hsa:117194 STRING: 9606.ENSP00000333800 UniGene: Hs.350566 |
