MRI1 Antibody

Datasheet

Code	CSB-PA014799GA01HU
Size	$600
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q9BV20

Target Names

MRI1

Alternative Names

EI2BL antibody; M1Pi antibody; Mediator of RhoA-dependent invasion antibody; Methylthioribose 1 phosphate isomerase 1 antibody; Methylthioribose 1 phosphate isomerase homolog antibody; Methylthioribose-1-phosphate isomerase antibody; MGC3207 antibody; MRDI antibody; mri1 antibody; MTNA antibody; MTNA_HUMAN antibody; MTR-1-P isomerase antibody; S methyl 5 thioribose 1 phosphate isomerase 1 antibody; S-methyl-5-thioribose-1-phosphate isomerase antibody; Translation initiation factor eIF 2B antibody; Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein antibody; Ypr118w antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human MRI1

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.

Gene References into Functions

Data indicate that the structural elements in MRDI distal from the MTR-1-P catalytic site are responsible for the invasion phenotype. PMID: 23859498
Identification of MRI1, encoding translation initiation factor eIF-2B subunit alpha/beta/delta-like protein, as a candidate locus for infantile epilepsy with severe cystic degeneration of the brain. PMID: 23124037

Subcellular Location

Nucleus. Cytoplasm. Cell projection. Note=Primarily nuclear, but cytoplasmic in cancer cells, with enrichment at leading edge of the plasma membrane in late stage tumor cells.

Protein Families

EIF-2B alpha/beta/delta subunits family, MtnA subfamily

Database Links

HGNC: 28469

OMIM: 615105

KEGG: hsa:84245

STRING: 9606.ENSP00000040663

UniGene: Hs.439370

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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