MRM3 Antibody, Biotin conjugated

Datasheet

Code	CSB-PA867196LD01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) MRM3 Polyclonal antibody

Uniprot No.

Q9HC36

Target Names

MRM3

Alternative Names

16S rRNA (guanosine(1370)-2'-O)-methyltransferase antibody; 16S rRNA [Gm1370] 2'-O-methyltransferase antibody; 4833420N02Rik antibody; AI255153 antibody; FLJ10581 antibody; HC90 antibody; MRM3 antibody; MRM3_HUMAN antibody; Putative RNA methyltransferase antibody; RMTL1 antibody; RNA methyltransferase like 1 antibody; RNA methyltransferase like protein 1 antibody; RNA methyltransferase-like protein 1 antibody; RP23-147P4.7 antibody; rRNA methyltransferase 3, mitochondrial antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human rRNA methyltransferase 3, mitochondrial protein (41-205AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Biotin

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1370 (Gm1370) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a conserved modification in the peptidyl transferase domain of the mtLSU rRNA.

Gene References into Functions

MRM2 and MRM3 are human mitochondrial methyltransferases involved in the modification of 16S rRNA and are important factors for the biogenesis and function of the large subunit of the mitochondrial ribosome. PMID: 25009282
Data show that 2'-O-methyltransferases MRM1, MRM2, and RNMTL1 are responsible for modification of large subunit rRNA at residues G1145, U1369, and G1370, respectively. PMID: 25074936
The ATF/CREB site is the key element for transcription of this protein found on human chromosome 17. PMID: 12296377

Subcellular Location

Mitochondrion.

Protein Families

Class IV-like SAM-binding methyltransferase superfamily, RNA methyltransferase TrmH family

Tissue Specificity

Expressed at same level in normal liver and hepatocarcinoma.

Database Links

HGNC: 18485

OMIM: 612600

KEGG: hsa:55178

STRING: 9606.ENSP00000306080

UniGene: Hs.182729

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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