MRPS18B Antibody

Code CSB-PA014892GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
Alternative Names
28S ribosomal protein S18-2 antibody; 28S ribosomal protein S18b antibody; 28S ribosomal protein S18b; mitochondrial antibody; C6orf14 antibody; DKFZp564H0223 antibody; HSPC 183 antibody; HSPC183 antibody; mitochondrial antibody; Mitochondrial ribosomal protein S18 2 antibody; Mitochondrial ribosomal protein S18B antibody; MRP S18 2 antibody; MRP S18 b antibody; MRP S18b antibody; MRP-S18-2 antibody; MRP-S18-b antibody; MRPS 18B antibody; MRPS18 2 antibody; Mrps18-b antibody; MRPS18B antibody; PTD017 antibody; RT18B_HUMAN antibody; S18amt antibody; S18mt-b antibody
Raised in
Species Reactivity
Human MRPS18B
Immunogen Species
Homo sapiens (Human)
Purification Method
Antigen Affinity purified
It differs from different batches. Please contact us to confirm it.
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Gene References into Functions
  1. Together, these data suggest that the S18-2 protein induces epithelial to mesenchymal cell transition through the TWIST2/E-cadherin signalling and, consequently, CXCR4-mediated migration of prostate cancer cells. PMID: 29396484
  2. Evolutionary trace analysis showed that the S18-2 protein is mutated at the higher rate in tumors, compared with S18-1 and S18-3. The one of the most conserved residues in the S18-2 protein sequence, Gly132, is often mutated in colorectal cancer. PMID: 27489352
  3. We conclude that high expression of S18-2 and free E2F...1might be a good set of prognostic markers for endometrial cancer PMID: 26959119
  4. Studies suggest that mitochondrial ribosomal protein S18-2 protein, together with the retinoblastoma protein (RB), plays a crucial role in the control on cell stemness and differentiation. PMID: 28361860
  5. S18-2 is a newly identified oncoprotein that may be involved in cancerogenesis PMID: 26023799
  6. EBNA-6 {ebna-3c} binds to MRPS18-2 , and targets it to the nucleus; binding targets the small pocket of pRb, which is a site of interaction with E2F1. The MRPS18-2 competes with the binding of E2F1 to pRb, thereby raising the level of free E2F1 PMID: 18391203

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Subcellular Location
Protein Families
Bacterial ribosomal protein bS18 family, Mitochondrion-specific ribosomal protein mS40 subfamily
Database Links

HGNC: 14516

OMIM: 611982

KEGG: hsa:28973

STRING: 9606.ENSP00000259873

UniGene: Hs.655329

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