MRPS30 Antibody

Code CSB-PA006740
Size US$100
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  • Western Blot analysis of LOVO cells using MRP-S30 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
MRPS30
Alternative Names
28S ribosomal protein S30 antibody; 28S ribosomal protein S30; mitochondrial antibody; Mitochondrial 28S ribosomal protein S30 antibody; mitochondrial antibody; Mitochondrial ribosomal protein S30 antibody; MRP S30 antibody; MRP-S30 antibody; MRPS30 antibody; PAP antibody; PDCD9 antibody; Programmed cell death 9 antibody; Programmed cell death protein 9 antibody; RT30_HUMAN antibody; S30mt antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the C-terminal region of Human MRP-S30.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:10000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Gene References into Functions
  1. data suggest that the strongest signal of association at 5p12 is mediated through coordinated activation of FGF10 and MRPS30, two candidate genes for breast cancer pathogenesis PMID: 27640304
  2. Among the 10 SNPs studied, rs10941679 in MRPS30 showed significant association with breast cancer risk when differences between the case and control groups in this Han Chinese population were compared. PMID: 24528085
  3. data suggest the 5p12 risk allele affects MRPS30 expression in estrogen-responsive tumor cells after tumor initiation by a mechanism affecting chromatin availability. PMID: 24388359
  4. The risk-associated allele of rs7716600 in the 5p12 ER-positive susceptibility locus was associated with elevated expression of the nearby gene MRPS30 and decreased MRPS30 promoter methylation exclusively in ER-positive tumors. eQTL and in vitro experiments suggest this allele affects MRPS30 expression in estrogen-responsive tumor cells after tumor initiation by a mechanism affecting chromatin availability. PMID: 24388359
Subcellular Location
Mitochondrion.
Protein Families
Mitochondrion-specific ribosomal protein mL65 family
Tissue Specificity
Heart, skeletal muscle, kidney and liver. Lower expression in placenta and peripheral blood leukocytes.
Database Links

HGNC: 8769

OMIM: 611991

KEGG: hsa:10884

STRING: 9606.ENSP00000424328

UniGene: Hs.124165

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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