MSL3 Antibody

Datasheet

Code	CSB-PA015042GA01HU
Size	$600
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Product Details
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Target Background

Product Details

Uniprot No.

Q8N5Y2

Target Names

MSL3

Alternative Names

MSL3 antibody; AU018931 antibody; DKFZp586J1822 antibody; Drosophila MSL3 like 1 antibody; Male specific lethal 3 (Drosophila) like 1 antibody; Male specific lethal 3 homolog (Drosophila) antibody; Male specific lethal 3 homolog 1 (Drosophila) antibody; Male specific lethal 3 homolog 1 antibody; Male specific lethal 3 homolog antibody; Male specific lethal 3 like 1 (Drosophila) antibody; Male specific lethal 3 like 1 antibody; Male specific lethal 3 protein like 1 antibody; Male-specific lethal 3 homolog antibody; Male-specific lethal-3 homolog 1 antibody; Male-specific lethal-3 protein-like 1 antibody; MS3L1_HUMAN antibody; MSL3 antibody; MSL3 like 1 antibody; MSL3-like 1 antibody; Msl31 antibody; MSL3L1 antibody; OTTHUMP00000022911 antibody; OTTHUMP00000022912 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human MSL3

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Has a role in chromatin remodeling and transcriptional regulation. Has a role in X inactivation. Component of the MSL complex which is responsible for the majority of histone H4 acetylation at 'Lys-16' which is implicated in the formation of higher-order chromatin structure. Specifically recognizes histone H4 monomethylated at 'Lys-20' (H4K20Me1) in a DNA-dependent manner and is proposed to be involved in chromosomal targeting of the MSL complex.

Gene References into Functions

MSL3 plays an important role in targeting the male specific lethal complex to chromatin in both humans and flies by binding to H4K20Me(1). PMID: 20943666
A multisubunit human histone acetylase complex that contains homologs of the Drosophila MSL proteins MOF, MSL1 (hampin A), MSL2, and MSL3 was described. This complex is responsible for histone H4 lysine-16 acetylation of all cellular chromosomes. PMID: 16227571

Subcellular Location

Nucleus.

Tissue Specificity

Expressed in many tissues including liver, pancreas, heart, lung, kidney, skeletal muscle, brain, and placenta, with highest expression in skeletal muscle and heart.

Database Links

HGNC: 7370

OMIM: 300609

KEGG: hsa:10943

STRING: 9606.ENSP00000312244

UniGene: Hs.655288

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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