MT1X Antibody

Datasheet

Code	CSB-PA17374A0Rb
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA17374A0Rb at dilution of 1:100 Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA17374A0Rb at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) MT1X Polyclonal antibody

Uniprot No.

P80297

Target Names

MT1X

Alternative Names

MT1X antibody; Metallothionein-1X antibody; MT-1X antibody; Metallothionein-IX antibody; MT-IX antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Metallothionein-1X protein (1-59AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The MT1X Antibody (Product code: CSB-PA17374A0Rb) is Non-conjugated. For MT1X Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA17374B0Rb	MT1X Antibody, HRP conjugated	ELISA
FITC	CSB-PA17374C0Rb	MT1X Antibody, FITC conjugated
Biotin	CSB-PA17374D0Rb	MT1X Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. May be involved in FAM168A anti-apoptotic signaling.

Gene References into Functions

Data show that in the MCF-7 breast cancer cell line, only MT1X metallothioneins (MTs) positively correlated with vascular endothelial growth factor C (VEGFC). PMID: 27107086
MT1XT20 Single Quasi-Monomorphic Mononucleotide Marker showing Microsatellite Instability is associated with Persian Lynch Syndrome PMID: 27797228
These findings suggest that functional interactions between FHL3 and MT-1X may provide some clues to the mechanisms of FHL3-regulated cell proliferation. PMID: 24690879
Results show variation in MTX1 is implicated in disordered gambling PMID: 22780124
siRNA-mediated knockdown of TCRP1 and MT1X was found to sensitize cells to cisplatin, leading to increased apoptosis and inhibition of cell proliferation PMID: 23251525
Our results suggest that MT1XT20 represents a sensitive and specific marker for MSI testing and could be included in a complete set of MSI markers for the confident identification of familial or sporadic dMMR patients in colorectal cancers. PMID: 22108904
It plays a role in the detoxification of heavy metals and reactive oxygen species. (review) PMID: 19881214

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Protein Families

Metallothionein superfamily, Type 1 family

Database Links

HGNC: 7405

OMIM: 156359

KEGG: hsa:4501

STRING: 9606.ENSP00000377995

UniGene: Hs.374950

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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