MTX1 Antibody

Code CSB-PA015211GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
MTX1
Alternative Names
MTX1; MTX; MTXN; Metaxin-1; Mitochondrial outer membrane import complex protein 1
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human MTX1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Involved in transport of proteins into the mitochondrion. Essential for embryonic development.
Gene References into Functions
  1. after the induction of apoptosis, Bak switches from its association with Mtx2 and VDAC2 to a closer association with Mtx1. PMID: 27845183
  2. Results describe the association between the MTX1 and beta-glucocerebrosidase genes and its possible effect on Parkinson disease. PMID: 21837367
  3. Single Nucleotide Polymorphism in metaxin 1 is associated with Gaucher disease PMID: 15024629
  4. The pathway of Voltage-dependent anion-selective channel biogenesis in human mitochondria involves the TOM complex, Sam50 and metaxins, and that it is evolutionarily conserved. PMID: 17510655
  5. mitofilin helps regulate mitochondrial morphology and at least four of the associated proteins (metaxins 1 and 2, SAM50 and CHCHD3) have been implicated in protein import PMID: 17624330

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Subcellular Location
Membrane; Single-pass type I membrane protein. Mitochondrion outer membrane.
Protein Families
Metaxin family
Database Links

HGNC: 7504

OMIM: 600605

KEGG: hsa:4580

STRING: 9606.ENSP00000357360

UniGene: Hs.490874

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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