MYO18B Antibody, HRP conjugated

Datasheet
Code CSB-PA815545LB01HU
Size US$299
Uniprot No. Q8IUG5
Protocols ELISA Protocol
Immunogen Recombinant Human Unconventional myosin-XVIIIb protein (370-512AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth.
Form Liquid
Conjugate HRP
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Unconventional myosin-XVIIIb, MYO18B
Immunogen Species Homo sapiens (Human)
Research Area Signal Transduction
Target Names MYO18B
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth.
Involvement in disease Klippel-Feil syndrome 4, autosomal recessive, with nemaline myopathy and facial dysmorphism (KFS4)
Subcellular Location Cytoplasm, Nucleus, Cytoplasm, myofibril, sarcomere
Protein Families TRAFAC class myosin-kinesin ATPase superfamily, Myosin family
Tissue Specificity Selectively expressed in cardiac and skeletal muscles. Weakly expressed in testis, pancreas, placenta, prostate, lung and thymus.
Database Links

HGNC: 18150

OMIM: 607295

KEGG: hsa:84700

STRING: 9606.ENSP00000334563

UniGene: Hs.417959

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